What is CGD?

Chronic granulomatous disease (CGD) is a genetic disorder in which white blood cells called phagocytes are unable to kill certain types of bacteria and fungi. People with CGD are constantly at risk of developing bacterial and fungal diseases that can be life-threatening.

Causes of CGD

CGD is caused by defects in an enzyme, NADPH Oxidase, which is essential for proper function of the immune system. These defects are linked to any one of five different genes, that are genetically inherited via the X chromosome.

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